Surgery Dosing Calculator

This unique HUMATE-P Surgery Dosing Calculator makes individual dosing fast, easy, and convenient. The calculator determines the correct HUMATE-P loading dose (measured in VWF:RCo units) needed to achieve the desired increase in circulating VWF, as defined in the product prescribing information. (For guidance on loading dose recommendations, please refer to Table 3 of the full prescribing information). All subsequent doses should be based on patient response and measured levels of VWF:RCo and FVIII.

These calculations are to be used only with HUMATE-P and are applicable for VWF:RCo loading dose calculations for the prevention of excessive bleeding during and after surgery for all types of VWD.

Calculate the Correct HUMATE-P Loading Dose

Instructions: To determine the HUMATE-P loading dose (as measured in VWF:RCo units) needed to achieve the target increase in circulating VWF:

  1. Enter the patient's body weight (BW) in kilograms (kg) OR pounds (lb)
  2. Enter the patient's baseline level (BL) of VWF:RCo (measured as IU VWF:RCo/dL)
  3. Enter the patient's target level (TL) of VWF:RCo (measured as IU VWF:RCo/dL)
  4. Enter the patient's in vivo recovery (IVR). IVR is measured as rise in IU/dL per IU/kg administered. If unknown, please click on the link next to the IVR field and a value of 2 IU/dL will be used as the default per the dosage instructions in the product prescribing information.
  • Click here to use a default value of 2.0
  • kg lb
  • Calculate

A full chart of the HUMATE-P Surgery Dosing Calculator for VWD is also available. General Rule: Doses are calculated based on an expected in vivo recovery of 2.0 IU/dL rise in VWF:RCo activity per every IU/kg of VWF:RCo administered.

You are now leaving the current website.

Do you want to continue?

No Yes